Dogs Combination: Homeopathic dilution of; Hard pad 30C Distemper 30C Leptospirosis 30C Hepatitis 30C Parvo Virus 30C Suggested use: One pillule twice daily for three days, Then one pillule weekly for six weeks, Then one pillule monthly for six months. This should be repeated every year. If in contact with disease take one pillule twice daily Nosodes are prepared by homeopathic dilution. Although they have been used for many years, they have not been subjected to clinical trials, so therefore the evidence for their prophylactic use can not be substantiated.